Tribulus terrestris (Tribuli Fructus) is a widely used medicinal herb in Traditional Medicine, known for its ability to promote Qi circulation, invigorate blood, pacify the Liver, dispel Wind, and support male and female reproductive health. Rich in biologically active compounds such as protodioscin, steroidal saponins, flavonoids, alkaloids, essential fatty acids and minerals, Tribulus terrestris is traditionally used to treat Liver Qi stagnation, visual disturbances, menstrual irregularities, fatigue, pain, and skin disorders. Modern research highlights its remarkable effects on enhancing natural testosterone production, improving sperm count and motility, supporting libido, reducing inflammation, increasing diuresis, protecting kidney function, and preventing stone formation. The herb also assists in regulating blood glucose, lowering triglycerides, improving cardiovascular circulation, and enhancing muscle strength and vitality. In East Asian traditional medicine, Tribulus is employed to relieve lumbar pain, headaches, breast distention, postpartum lactation issues, urticaria, sore throat due to stagnation, and a range of disorders involving Qi and Blood imbalance. With its bitter–slightly pungent property and affinity for the Liver and Lung meridians, Tribulus terrestris is considered a versatile therapeutic agent used in formulas for liver–kidney nourishment, blood activation, reproductive support, and overall wellness enhancement. Understanding its medicinal properties, chemical constituents, recommended dosage, and safe usage allows for effective application of this valuable herb in daily health maintenance.